Saturday, November 29, 2008

Risk Factors (Page 3)

There are appear to be several reasons for artery injuries (lesions) and inflammation, followed by plaque build up. The arteries are under pressure as the heart beats, and places where junctions and bends occur can create mechanical stress and turbulence. These are thought to be a basis for early injury. You might have seen water in a stream as it swirls around rocks, causing similar turbulence. Plus, the heart beats; it moves and flexes constantly, so the arteries move with every beat!

What seems to happen is that the artery’s thin, inner layer (the endothelium) gets stressed and injured. The body attempts to repair the injury or lesion but the process can keep going, creating a problem inside a small space! Here is a link to a graphic of artery plaque and its growth (remember it's only about 1/8" in diameter). It shows early years at the top and later years toward the bottom (will open a new window): http://upload.wikimedia.org/wikipedia/commons/9/9a/Endo_dysfunction_Athero.PNG

In addition, many of us have contributing (or risk) factors that can add inflammation, such as:
age
high blood pressure
high cholesterol
overweight/obesity
diabetes
smoking
gum disease/infections
stress

lack of sleep

There are other possible risk factors but the above list has the major ones. I know this can seem daunting! The process of plaque growth is complex, and the risk factors seem like a part of daily life. And you're right! The risk factors on the above list (except age) largely reflect our choices, and are often related to each other. That also means that you can manage them, more simply then you might think. When you do, you will have better overall health, energy, and longevity!

To manage plaques, it’s important to keep inflammation low. That’s why health professionals have recommended a small, 81 mg. coated aspirin daily (aspirin has both anti-inflammatory and anti-clotting properties), along with other eating and lifestyle improvements, such as cutting saturated fat and refined carbs, and controlling other risk factors.

A significant component of plaque is oxidized LDL. Oxidized LDL is created by free radicals (unstable molecules) that turn the LDL rancid (like rancid oil or butter, which are also oxidized). This LDL is more toxic and sticky in the bloodstream. Our immune system sees the oxidized LDL as foreign and it attacks the molecule with white cells inside the artery wall where the particles stick.

To minimize LDL oxidation (picture an apple or avocado turning brown after its cut), take more antioxidants. Antioxidants will help to replace the missing oxygen molecule in free radicals, helping to minimize oxidation, including LDL oxidation.

Helpful tip: Vitamins A/beta carotene, C , E, K, selenium, etc., are all antioxidants, and taking a quality, bio-available multivitamin and mineral supplement will give you some foundational amounts (they work together more effectively). Plus, colorful fruits and vegetables (which can also help stabilize blood sugar) have antioxidant effects: think green, yellow, orange, red, blue, purple, etc.

For example, fruits and natural juices like acai, pomegranate, and blueberry have good antioxidant (free radical) capabilities. And there has been research that free radicals contribute to our aging, including our skin, joints, and organs. Yes, wrinkles too, so looking your best reflects feeling your best!

Here is a recent article on juices (will open a new window): http://www.reuters.com/article/healthNews/idUSCOL65673220080516 For a healthy beverage besides coffee or soda, several cups of green (or white) tea can offer beneficial flavanols (antioxidants).

Disclaimer: The information contained on this website is for education and is not intended as a substitute for the diagnosis, treatment or advice of a licensed professional. Statements regarding the properties or functions of nutritional supplements may not have been evaluated by the Food and Drug Administration and not intended to diagnose, treat, cure or prevent any disease.
© 2008-2010 by Steve/Beat Heart Disease